不公开 发表于 2025-3-25 04:29:55
ns. The proven scalability of the technology combined with the modular nature provides unmatched versatility. Extrusion has been utilized for dispersion manufacturing of commercial products across a range of scales and integrating with in-line monitoring technologies, it fully enables the benefits o认识 发表于 2025-3-25 07:37:04
uch as particle size reduction, use of solubilizers, and complexing agents, in addition to lipid formulations, have been conventionally used but with limited success. When such approaches fail to provide desired bioavailability, amorphous formulations can be used as an alternate approach. However, a名字的误用 发表于 2025-3-25 11:56:45
n this book, the formulation scientist would benefit from a priori knowledge whether the amorphous route is a viable one for a given drug and how much solubility improvement, and hence increase in bioavailability, can be expected, and what forms of solid dispersion have been developed in the past. I有机体 发表于 2025-3-25 17:59:55
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considerations, while the use of thermodynamics combined with the notion of a continuous density profile at the interface between a liquid and its vapor is mainly due to van der Waals. The formal statistical mechanics of inhomogeneous fluids is now well developed and is finding a number of applicatitenosynovitis 发表于 2025-3-26 06:07:37
utional impurities, vacancies, etc., of liquids and liquid mixtures, and finally of metastable phases such as glasses, requires the solution of the Schrödinger equation for 10. electrons, all interacting with one another and with the positive ions. For a perfect crystal, Bloch’s theorem allows us to少量 发表于 2025-3-26 09:11:55
eory of freezing of some simple liquids. This is closely related to the theory of the bulk liquid structure, the main topic of the first part of this chapter. Here, the so-called Born—Green—Yvon hierarchy is the starting point of all structural theories of simple liquids. This hierarchy was also useScleroderma 发表于 2025-3-26 15:34:07
of the key ideas of amorphous magnetism to well-established concepts of magnetism in crystalline solids, stressing the points where something new emerges because of the lack of a crystal lattice. For example, there are many amorphous ferromagnets yet no amorphous antiferromagnets are known to exist表否定 发表于 2025-3-26 16:58:57
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