菊花 发表于 2025-3-28 17:03:27
http://reply.papertrans.cn/43/4251/425005/425005_41.pngCommodious 发表于 2025-3-28 19:37:44
,Eukaryotic HSP60: A “danger signal” for T- and natural killer cells,hown that HSP purified from tumour and virus infected cells are also capable of eliciting a protective CTL-mediated immunity [.- .]. Preparations of HSP70 and gp96 are able to activate antigen specific T-cells and the uptake of HSP/peptide complexes is most likely mediated by receptors that are expr委派 发表于 2025-3-29 00:33:44
Heat shock proteins and experimental arthritis,sive and destructive features [.]. As yet, the underlying pathogenic mechanisms of RA remain poorly understood. In order to help gain a better understanding of the disease, several animal models of RA have been developed and have been widely studied. Although these models can be very instructive, no鸟笼 发表于 2025-3-29 04:50:22
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The development of immune therapy with HSP60 for juvenile idiopathic arthritis,sts a dysfunction in the immune regulation, while a spontaneous relapse or remission of disease suggests a successful immune-regulatory process. Understanding the regulatory mechanisms that control the balance between immunity and tolerance can provide potential new targets for therapeutic interventIncisor 发表于 2025-3-29 12:15:56
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http://reply.papertrans.cn/43/4251/425005/425005_47.pngincubus 发表于 2025-3-29 22:32:49
Immunity to heat shock proteins and atherosclerosis,cific immune responses. In this chapter, we will describe early atherosclerosis as an autoimmune disorder and heat shock protein 60 (HSP60) as the culprit-autoantigen. After a brief review of experimental . data and results from animal experiments, we will focus on clinical data confirming our patho发微光 发表于 2025-3-30 03:56:21
Chaperonins: Chameleon proteins that influence myeloid cells,es, plastids and mitochondria and the TCP-1 subfamily found in eukaryotes and the . This chapter will focus on the GroE subfamily which consists of two members: chaperonin (Cpn)60 and the co-chaperone — Cpn10. Both proteins form oligomeric structures required for protein folding [.] and the mechanis钝剑 发表于 2025-3-30 06:46:17
Heat shock protein receptors, functions and their effect on monocytes and dendritic cells,or folding intermediate polypeptides, chaperons prevent misfolding and aggregation, and promote folding and translocation [.]. Human and microbial HSP70 consist of an N-terminal ATPase fragment of 44 kD and a C-terminal peptide-binding fragment of 28.5 kD. HSP70 is a highly conserved protein among v