IDEAS
发表于 2025-3-26 21:54:57
Varieties of Mathematical Experiencet in the setting of suppressive combination antiretroviral therapy (cART) and to develop and evaluate novel strategies for more definitive treatment of HIV infection (i.e., viral eradication “cure”, or sustained off-cART remission). Multiple different NHP models are available, each characterized by
zonules
发表于 2025-3-27 03:12:02
Interviewing Perpetrators of Genocide,SIV are lentiviruses that infect CD4+ lymphocytes in addition to myeloid cells in blood and tissues. HIV infection of myeloid cells in brain, lung, and heart causes tissue-specific diseases that are mostly observed during severe immunosuppression, when the number of circulating CD4+ T cells declines
Guaff豪情痛饮
发表于 2025-3-27 08:00:45
Role and Function of Company Lawyers,blishment, maintenance, and potential clearance of latent infection are complex dynamic processes and can be best understood and described with the help of mathematical models. Here we review the use of viral dynamics models for HIV, with a focus on applications to the latent reservoir. Such models
离开就切除
发表于 2025-3-27 11:21:33
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Altitude
发表于 2025-3-27 16:57:44
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绕着哥哥问
发表于 2025-3-27 19:54:46
Matt Kaeberlein,Lara S. Shamieho emerging. Cell and gene therapy strategies are connected with human pathologies at a fundamental level, by delivering DNA and RNA molecules that could correct and/or ameliorate the underlying genetic factors of any illness. The history of HIV gene therapy is especially intriguing, in that the viru
破裂
发表于 2025-3-28 00:39:15
Molecular Control of HIV and SIV Latency, at the transcriptional and post-transcriptional levels. A better understanding of latency is needed in order to ultimately achieve a cure for HIV. The mechanisms underlying latency vary between patients, tissues, anatomical compartments, and cell types. From this point of view, simian immunodeficie
dapper
发表于 2025-3-28 02:49:54
Assays to Measure Latency, Reservoirs, and Reactivation,ently infected resting CD4. T cells carrying an integrated copy of the viral genome that is not expressed while the cells remain in a resting state. Targeting this latent reservoir is a major focus of HIV-1 cure research, and the development of a rapid and scalable assay for the reservoir is a rate-
EXUDE
发表于 2025-3-28 08:32:38
The Antiviral Immune Response and Its Impact on the HIV-1 Reservoir,HIV-1 infection unless these cells are eliminated. Latently infected cells probably do not express viral antigens and thus may not be susceptible to the HIV-1 specific immune response, nevertheless the size and composition of the reservoir is influenced by the immune system. In this chapter, we revi
注意到
发表于 2025-3-28 13:12:24
Nonhuman Primate Models for Studies of AIDS Virus Persistence During Suppressive Combination Antiret in the setting of suppressive combination antiretroviral therapy (cART) and to develop and evaluate novel strategies for more definitive treatment of HIV infection (i.e., viral eradication “cure”, or sustained off-cART remission). Multiple different NHP models are available, each characterized by