Confess 发表于 2025-3-30 09:06:47
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ABCA1, ABCG1, and Cholesterol Homeostasis,ulation is toxic to cells and constitutes the molecular basis for many diseases, especially atherosclerotic cardiovascular disease. Thus, cellular cholesterol is tightly regulated to maintain a homeostasis. Reverse cholesterol transport (RCT) is thought to be one primary pathway to eliminate excessi脖子 发表于 2025-3-30 21:22:50
HDL and Diabetes,our-fold increased risk of developing cardiovascular disease. This chapter focuses on the anti-diabetic and cardioprotective functions of plasma high-density lipoproteins (HDLs). HDLs and the main HDL apolipoprotein, apoA-I, improves pancreatic beta cell function. ApoA-I also improves insulin sensitpalpitate 发表于 2025-3-31 03:10:12
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HDL Mimetic Peptides,w to improve HDL function rather than its plasma level has become a new focus of scientists’ attention. Numerous HDL mimetic peptides have been designed and investigated in various animal models in recent years. Although the underlying mechanisms are not fully understood, the peptides’ antiatherogenAntarctic 发表于 2025-3-31 11:45:30
HDL and microRNAs,to prevent several metabolic diseases. Besides the classic genes regulating cholesterol efflux and reverse cholesterol transport (RCT), microRNAs (miRNAs) could also affect HDLs biogenesis, metabolism, and functions. This chapter summarizes the miRNAs, which regulate HDLs functions in table. In addicurriculum 发表于 2025-3-31 13:45:18
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