Oafishness 发表于 2025-3-30 10:08:14
https://doi.org/10.1007/978-3-662-01556-8tis. This involved a decrease in the amount of galactose on the Fc biantennary oligosaccharides resulting in chain termination with N-acetylglucosamine. We have shown similar changes in two animal models of arthritis (i) where DBA/1 mice were immunised with type II collagen and (ii) in the spont清真寺 发表于 2025-3-30 15:36:51
https://doi.org/10.1007/978-3-642-99416-6 labelled and oligosaccharides (Oxford Glycosystems) and the other is based on high pH anion exchange, coupled with electrochemical detection (Dionex Carbohydrate System), which allows determination of the monosaccharide composition as well as mapping of the oligosaccharide moieties.FOR 发表于 2025-3-30 16:49:43
Lehrbuch der Animalischen Physiologieed . This study also showed that the percentage incidence of agalactosyl structures on the bi-antennary oligosaccharide complex linked to the Fc region, was increased in patients with rheumatoid arthritis. An earlier study , published in abstract form only, had also suggested that this was theBOOM 发表于 2025-3-30 20:49:05
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,β1,4-Galactosyltransferase Variations in Rheumatoid Arthritis,the interrelationship between reduced galactosylation of the oligosaccharides of IgG, auto-sensitization to which is thought to be of central importance in the pathogenesis of rheumatoid arthritis (RA), and the enzyme β 1,4-Galactosyltransferase (GTase) that catalyses the addition of galactose to the oligosaccharide chains on this molecule.