悠然 发表于 2025-3-23 11:28:43
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Signaling Determinants of Glioma Cell Invasion, integrins that initiate diverse intracellular signalling pathways. Key signaling elements stimulated by integrins include PI3K, Akt, mTOR and MAP kinases. In order to detach from the tumor mass, glioma cells secrete proteolytic enzymes that cleave cell surface adhesion molecules, including CD44 andJAUNT 发表于 2025-3-24 01:27:33
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STAT Signaling in Glioma Cells,e number of human tumors, including gliomas and may contribute to oncogenesis. In this chapter, we have (1) summarized the mechanisms of STAT activation in normal and malignant signaling; (2) discussed evidence for the critical role of constitutively activated STAT3 and STAT5 in glioma pathobiology;anaerobic 发表于 2025-3-24 13:08:29
Cannabinoid Signaling in Glioma Cells,ction in tumor cells. Induction of cell death by cannabinoid treatment relies on the generation of a pro-apoptotic sphingolipid ceramide and disruption of signaling pathways crucial for regulation of cellular proliferation, differentiation or apoptosis. Increased ceramide levels lead also to ER-stre确认 发表于 2025-3-24 15:37:32
James M. Suttie,Peter F. Fennessyolvement of purinergic signalling in the pathophysiology of the CNS, including trauma, ischaemia, epilepsy, neurodegenerative diseases, neuropsychiatric and mood disorders, and cancer, including gliomas.OVER 发表于 2025-3-24 20:54:45
Equipment for Protected Cropping Structures,alcium signal generation will be discussed in-depth, to show complexity of machinery engaged in formation of this signal. Moreover, possible mechanisms of modulation of the calcium signal in diverse environments there will be presented herein. Finally, the possible role of calcium signal in glioma mcrumble 发表于 2025-3-24 23:24:50
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