音乐等 发表于 2025-3-26 21:36:42
Glioma Signaling978-3-030-30651-9Series ISSN 0065-2598 Series E-ISSN 2214-8019Barter 发表于 2025-3-27 01:31:56
https://doi.org/10.1007/978-3-030-30651-9secondary messengers; nucleotide receptors; tumor growth; tumor invasion; tyrosine kinase receptors; Receneutral-posture 发表于 2025-3-27 09:11:33
https://doi.org/10.1007/978-3-663-05361-3(P1) and P2 nucleotide receptors in the brain on both neurons and glial cells. Adenosine receptors play a major role in presynaptic neuromodulation, while P2X ionotropic receptors are involved in fast synaptic transmission and synaptic plasticity. P2Y G protein-coupled receptors are largely involvedcurriculum 发表于 2025-3-27 12:02:05
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Hormones and Aggressive Behavior glioma C6 cells. P2Y. and P2Y. both respond to ADP, but while P2Y. links to PLC and elevates cytosolic Ca. concentration, P2Y. negatively couples to adenylate cyclase, maintaining cAMP at low level. In glioma C6, these two P2Y receptors modulate activities of ERK1/2 and PI3K/Akt signaling and the eWallow 发表于 2025-3-27 20:23:21
Diabetes mellitus and atherosclerosisto the cytoplasmic calcium binding effectors. Calcium signal is fast and due to diversity of calcium binding proteins it may have a very broad effect on cell behavior. Being a crucial player in neuronal transmission it is also very important for glia physiology. It is responsible for the cross-talkBAIT 发表于 2025-3-28 00:03:17
R. Tsujimura,N. Kariyama,N. Hatotanirmed in ., . and . glioma models indicate that alterations in the purinergic signaling are involved in the progression of these tumors. Gliomas have low expression of all E-NTPDases, when compared to astrocytes in culture. Nucleotides induce glioma proliferation and ATP, although potentially neuroto肉身 发表于 2025-3-28 05:11:53
Robert I. Nicholson,Julia M. W. Geeoskeleton dynamics in glioma C6 cells. P2Y.R coupled with G-proteins, in response to ATP or UTP, regulates the level of iphosphatidylinositol-4,5-bisphosphate (PIP.) which modulates a variety of actin binding proteins and is involved in calcium response and activates Rac1 and RhoA proteins. The RhoA中和 发表于 2025-3-28 07:06:25
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https://doi.org/10.1007/978-3-030-93691-4 (RTK) is a tyrosine kinase located at the cellular membrane and is activated by binding of a ligand via its extracellular domain. Protein phosphorylation by kinases is an important mechanism for communicating signals within a cell and regulating cellular activity; furthermore, this mechanism functi