Debark 发表于 2025-3-30 09:59:34
https://doi.org/10.1007/978-3-658-13145-6well understood. In an attractive working model for long-range order in metaphase chromosomes the DNA is constrained by scaffold proteins into loops of average size 50 kbps [.]. These loops are packaged by the histones H1, H2A, H2B, H3 and H4 into nucleosomes and higher order chromatin structures.justify 发表于 2025-3-30 12:49:33
,Wählerverhalten und Wahlforschung,ranscription of specific genes. However, it has also become clear that the transcription of eukaryotic genes always requires complex assemblies of several different proteins in addition to RNA polymerase. Protein-protein as well as protein-DNA interactions are of crucial importance in transcription.突袭 发表于 2025-3-30 18:03:05
,Genome Structure — Function from Nuclei to Chromosomes and Nucleosomes,t different levels of organization is strictly related to the cell functioning (see also the chapters by Stein, Wolffe, Beato, Gilmour, Turner in this volume), but large uncertainty still exists on the higher order chromatin-DNA structures..