不容置疑 发表于 2025-3-26 23:01:11

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GUILT 发表于 2025-3-27 01:17:16

Manfred Schwab,Hartmut M. Rabes,Hans Peter Hofschn

忘川河 发表于 2025-3-27 06:53:50

https://doi.org/10.1007/978-3-030-63197-0the proportions of fatal cancers attributable to alcohol and ionizing radiation, and reasonable guesses can be made at the maximum effect of some of the other categories..Many of the factors act synergistically with one another, so that the risk of developing specific cancers can be modified in diff

RENIN 发表于 2025-3-27 11:33:08

https://doi.org/10.1007/978-1-349-09402-8ssor gene provide important clues for cancer risk assessment in molecular epidemiology. For example, characteristic . mutation spectra have been associated with: dietary aflatoxin B. exposure and hepatocellular carcinoma; sunlight exposure and skin carcinoma; and cigarette smoking and lung cancer. T

摘要记录 发表于 2025-3-27 15:20:18

Caroline Cummings,William O’Donohuedeletion of GSTM1 (GSTM1-0) and lung cancer (odds ratio: 1.41; 95% CI: 1.23-1.61). Combination of GSTM1-0 with two allelic variants of cytochrome P4501A1 (CYP1A1), CYP1A1 m2/m2 and CYP1A1 Val/Val further increases the risk for lung cancer. Indirect mechanisms by which deletion of GSTM1 increases ris

definition 发表于 2025-3-27 19:31:51

https://doi.org/10.1007/978-0-387-72171-2predisposing genes can then be used as intermediate risk markers rather than taking cancer as an endpoint. In case-control studies, simultaneous measurements were carried out in each subject to determine exposure/early effect markers, e.g. polycyclic aromatic hydrocarbons (PAH)-DNA adducts, and susc

animated 发表于 2025-3-28 00:00:40

Madness Itself: the Real Story,tGua), for example, differ only by one CH. group. These lesions are formed in DNA upon exposure to N-methyl-N-nitrosourea (MeNU) or N-ethyl-N-nitrosourea (EtNU), both of which induce mammary adenocarcinomas in female rats at high yield. Unrepaired O.-alkylguanines cause transition mutations via misp

确定的事 发表于 2025-3-28 03:21:09

Cultural Constructions of the Femme Fataleth the rapid and efficient removal of lesions that block transcription and thus need to be eliminated urgently (transcription-coupled repair, TCR). The other accomplishes the slower and less efficient global genome repair (GGR) of bulk DNA, including the nontranscribed strand of active genes.

FIN 发表于 2025-3-28 09:29:58

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facilitate 发表于 2025-3-28 14:01:38

Borders, Boundaries and Difference, investigated at the molecular level. It extends over a broad region of possibly 500 kb, and no trinucleotide or other simple repeat motifs have been identified in the region. FRA3B has recently been shown to lie within the . gene locus. This region and the . gene are unstable in a number of tumors
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查看完整版本: Titlebook: Genes and Environment in Cancer; Manfred Schwab,Hartmut M. Rabes,Hans Peter Hofschn Conference proceedings 1998 Springer-Verlag Berlin · H