麻烦 发表于 2025-3-21 17:26:41

书目名称Gene and Cellular Immunotherapy for Cancer影响因子(影响力)<br>        http://figure.impactfactor.cn/if/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer影响因子(影响力)学科排名<br>        http://figure.impactfactor.cn/ifr/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer网络公开度<br>        http://figure.impactfactor.cn/at/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer网络公开度学科排名<br>        http://figure.impactfactor.cn/atr/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer被引频次<br>        http://figure.impactfactor.cn/tc/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer被引频次学科排名<br>        http://figure.impactfactor.cn/tcr/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer年度引用<br>        http://figure.impactfactor.cn/ii/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer年度引用学科排名<br>        http://figure.impactfactor.cn/iir/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer读者反馈<br>        http://figure.impactfactor.cn/5y/?ISSN=BK0382002<br><br>        <br><br>书目名称Gene and Cellular Immunotherapy for Cancer读者反馈学科排名<br>        http://figure.impactfactor.cn/5yr/?ISSN=BK0382002<br><br>        <br><br>

钳子 发表于 2025-3-21 21:34:42

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dearth 发表于 2025-3-22 00:49:49

Biology of CAR-T Cellsin patients with hematologic malignancies, leading to the FDA approval of five CAR-T cells for relapsed or refractory B cell malignancies. The components of these CARs (the extracellular antigen-binding domain, hinge and transmembrane region, co-stimulatory domains, and activation domain) were metho

首创精神 发表于 2025-3-22 05:36:20

Cell Types Used for CAR Generationcer patient. Although this personalized autologous T-cell manufacturing method has many advantages and has resulted in outstanding clinical data in hematologic malignancies, a number of aspects require improvement for cell therapy to impact broader patient populations. The first aspect relates to th

Admonish 发表于 2025-3-22 09:07:11

Combination Therapeutics with CAR-T Cell Therapyultiple hematological malignancies with potential for long term cure. However, multiple hurdles remain to be overcome. Some issues are inherent to CAR-T cells, such as suboptimal expansion, rapid exhaustion, or rejection. Other problems are related to the immunosuppressive tumor microenvironment, wh

Servile 发表于 2025-3-22 15:58:34

Safety Switches Used for Cellular Therapiestimes fatal complications. Safety switches are increasingly used to manage serious side effects associated with these advanced cellular therapies. In this chapter, we review safety switches categorized in three classes: (a) metabolic (gene-directed enzyme prodrug therapy, GDEPT), (b) dimerization-in

Servile 发表于 2025-3-22 19:27:25

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Autobiography 发表于 2025-3-22 23:01:05

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沉思的鱼 发表于 2025-3-23 03:13:43

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披肩 发表于 2025-3-23 06:38:36

Bringing CAR-T to the ClinicA) approval was in 2017 for CD19-directed CAR-T cell therapy using tisagenlecleucel (tisa-cel) for the treatment of pediatric patients (up to age 25) with relapsed or refractory (R/R) B-acute lymphoblastic leukemia (B-ALL). That same year, CD19 CAR-T cell therapy with axicabtagene ciloleucel (axi-ce
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