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Tumor Suppressor Genes,for human cancers (Friend et al. 1986) . The functional groundwork for the efficacy of this avenue of approach came from studies on the genetics of cancer using somatic cell genetics. The first report, in 1969, of the suppression of malignancy in hybrid cells between tumorigenic and nontumorigenic mSubstitution 发表于 2025-3-22 10:43:58
Oligonucleotide Therapeutics for Human Leukemia,sible for cell growth, development, and neoplastic transformation. With this knowledge has come a natural desire to translate this information into new therapeutic strategies for many of the common maladies which afflict humankind. These include in particular, but are not limited to, cardiovascular,chastise 发表于 2025-3-22 16:30:59
Ribozymes as Biotherapeutic Tools for the Modulation of Gene Expression,process of genetic alterations of oncogenes and/or tumor suppressor genes (Foulds 1958; Fearon and Vogelstein 1990). Small molecules interfering with genetic deregulation might become key players in the future search for new anti—cancer drugs. Examples of such molecules include antisense oligonucleochastise 发表于 2025-3-22 19:25:38
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