Mutter
发表于 2025-3-28 16:56:17
Transcription: The Never Ending Storyealing montages of the remarkably complex yet elegant consequences of evolution. Transcription research started from humble beginnings with the isolation of 3 distinct RNA polymerases. This was followed by a rich period of mapping promoters, enhancers and the isolation of the first sequence specific
occurrence
发表于 2025-3-28 20:57:20
The General Transcription Machinery and Preinitiation Complex Formationitiation of transcription and requires a host of accessory proteins, termed general transcription factors (GTFs), to commence basal level transcription dictated by the core promoter elements. The GTFs for pol II-mediated transcription include TFIIA, TFIIB, TFIID, TFIIE, TFIIF, and TFIIH. The transcr
浮雕
发表于 2025-3-29 01:57:37
The Dynamic Association of RNA Polymerase II with Initiation, Elongation, and RNA Processing Factorsted general transcription factors (GTFs), including TBP, TFIIB, TFIIF, and TFIIH are sufficient for recognition and low levels of accurate transcription from common core promoter elements . (. and .). However, in addition to these factors necessary for basal transcription initiation, accurately regu
output
发表于 2025-3-29 07:01:17
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collagen
发表于 2025-3-29 09:00:06
Chromatin and Regulation of Gene Expressionmeters. The organization of this entity within the confines of a nucleus is an essential challenge for every eukaryotic cell. Darkly staining nuclear material was observed by early microscopists and called chromatin, which later proved to be the structural answer to this problem. Chromatin structure
展览
发表于 2025-3-29 11:46:00
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penance
发表于 2025-3-29 15:50:59
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忧伤
发表于 2025-3-29 20:49:01
Transcriptional Repressors and Repression Mechanismsrn formation, tissue differentiation, and normal development. In this chapter, we will use well-understood cases to provide an overview of the molecular mechanisms by which transcription factors mediate repression.
Expertise
发表于 2025-3-30 00:03:04
STATs in Cytokine-mediated Transcriptional Regulationytokines and growth factors to regulate transcription. Upon stimulation, STATs become tyrosine phosphorylated to form functional dimers. Activated STAT dimers then translocate into the nucleus where they directly bind to the promoters of downstream genes to activate transcription. Posttranslational
SHOCK
发表于 2025-3-30 07:51:57
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