不爱防注射
发表于 2025-3-25 05:32:51
R. Francisco,C. Uribe,S. Ignacio,R. Vázquez damage sensation and repair, genotoxic stress, neoplasia, and molecular epigenetics. The genes were originally identified in in vitro screens of irradiation- and interleukin-induced transcription and have since been implicated in a host of normal and aberrant central nervous system processes. These
Bother
发表于 2025-3-25 09:34:37
978-3-030-94806-1The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
organic-matrix
发表于 2025-3-25 12:39:41
Gadd45 Stress Sensor Genes978-3-030-94804-7Series ISSN 0065-2598 Series E-ISSN 2214-8019
充满人
发表于 2025-3-25 18:42:10
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Ambulatory
发表于 2025-3-25 22:09:55
Roles for GADD45 in Development and Cancer,ng DNA repair, cell cycle arrest, and apoptosis. Here, we review current literature investigating GADD45 family members as they relate to normal development and carcinogenesis. We first describe how modulation of GADD45 in model organisms has facilitated our understanding of roles for GADD45 family
纬度
发表于 2025-3-26 03:53:11
Gadd45 in Normal Hematopoiesis and Leukemia,normal blood cell development and leukemia. Each of the Gadd45 genes was shown to be regulated independently in myeloid cells in response to cytokine stimulation modulating blood cell survival and differentiation, including maintaining the quiescent stem cell pool. Gadd45a and Gadd45b were also show
Mammal
发表于 2025-3-26 04:59:35
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ACTIN
发表于 2025-3-26 08:45:58
Gadd45 Proteins in Immunity 2.0,es has to distinguish between self and non-self, but also between harmless and dangerous. To do so, the immune system developed an innate and an adaptive branch that provide immediate and long-lasting protection, respectively. Furthermore, the immune system is composed of different cell types, which
使迷惑
发表于 2025-3-26 16:16:50
Gadd45 in the Liver: Signal Transduction and Transcriptional Mechanisms,er methylation frequently silences Gadd45β, due to a suppressive function that is often proapoptotic. In normal hepatocytes, Gadd45β facilitates cell survival, growth, and proliferation. Gadd45β binds MKK7—downstream of TNFα and its receptors—to prevent this kinase from activating JNK2. Hence, the .
中止
发表于 2025-3-26 18:52:56
Gadd45 in Preeclampsia,, inflammatory cytokines, and oxidative stress were reported as contributing factors to the preeclamptic pathology. Seeking common sensors of various stressors in preeclampsia is of new interest and can potentially benefit in disease prevention and treatment. Recent studies have highlighted the role