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https://doi.org/10.1007/978-3-319-67759-0 extracellular matrix (ECM). If the chondrocytes excessively degrade the components, osteoarthritis (OA) issue is raised for a progressive degradation of articular cartilages in the tissue. Rheumatoid arthritis (RA) is another type of OA but a type of autoimmune disease with chronic inflammation res