小平面 发表于 2025-3-30 10:18:55
Non-MAX Phase Precursors for MXeneshe heptahelical domains are forced to change their relative position, which within the dimer leads to consecutive activation of single heptahelical domain. This heptahelical domain than in turn activates G-proteins, most likely in similar manner as in case of GPCRs from other families (that may be fDiskectomy 发表于 2025-3-30 16:05:37
https://doi.org/10.1007/978-3-031-58144-1g the receptor dimer interface, and this appears to be dependent on membrane cholesterol content. This gives rise to the exciting and challenging possibility of age and tissue dependence of drug efficacy. We envision that GPCR oligomerization could be a game changer in future drug discovery.Notorious 发表于 2025-3-30 20:16:48
978-3-319-86795-3Springer International Publishing AG 2017FISC 发表于 2025-3-30 20:44:12
G-Protein-Coupled Receptor Dimers978-3-319-60174-8Series ISSN 1048-6909 Series E-ISSN 2524-6488Mobile 发表于 2025-3-31 01:29:37
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