duodenum 发表于 2025-3-21 17:37:22

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圣人 发表于 2025-3-21 20:21:21

Xinfeng Zhao,Qian Li,Jia QuanDescribes progress in functional immobilization of G protein-coupled receptor.Addresses pharmacological parameters in protein-drug interactions.Reviews the applications of protein immobilization

Intrepid 发表于 2025-3-22 02:30:39

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Indict 发表于 2025-3-22 05:56:30

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BOOR 发表于 2025-3-22 09:27:41

,Wordsworth’s ‘Leveling’ Muse in 1798,sirable way to immobilize GPCRs on solid surfaces is oriented immobilization. In this way, the receptors can be optimal in their orientation, conformation, and activity or functional studies. In this chapter, we review the affinity-based non-covalent and site-specific covalent immobilization methods

amnesia 发表于 2025-3-22 14:05:00

The Informal Logic of Mathematical Proof,ts in practice. This makes it critical to fundamental research of understanding biological processes and the efforts to develop new therapeutic molecules. In this chapter, we summarize several key biochemical parameters, such as binding affinity and kinetics, dynamic conformational ensembles of drug

amnesia 发表于 2025-3-22 20:58:04

https://doi.org/10.1007/978-3-642-73589-9f additional examples of new approaches and/or applications for decoding the interaction between drugs and GPCRs have appeared. In this chapter, we present some of the reports using immobilized GPCRs for drug-receptor interaction analysis, including labelled and label-free assays.

虚构的东西 发表于 2025-3-22 22:47:48

180 Keywords Geld- und Währungsrechtpound libraries and natural product extracts are the widely used two sources for bioactive compound screening. In this chapter, we aim to review some representative immobilized GPCR-based methods for the discovery of the bioactive compounds targeting the receptors, which may provide insight into the

白杨 发表于 2025-3-23 04:37:17

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GLUE 发表于 2025-3-23 08:18:35

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查看完整版本: Titlebook: G Protein-Coupled Receptors; Immobilization and A Xinfeng Zhao,Qian Li,Jia Quan Book 2023 The Author(s), under exclusive license to Springe