Stimulant 发表于 2025-3-21 17:40:21
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Exosomes: Biogenesis, Composition, and Synthesis,ation of early endosomes that develop into multivesicular bodies (MVBs) is a key step in this process. These MVBs may merge with lysosomes to be degraded, or they can fuse with the plasma membrane and release their intraluminal vesicles (ILVs) as exosomes. Proteins, lipids, and nucleic acids includiCorroborate 发表于 2025-3-22 04:09:14
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,Therapeutic Impact of Exosomes on Huntington’s Disease,psychiatric problems. HD is predominantly caused by a genetic mutation that results in the abnormal production of a protein called huntingtin, which leads to the degeneration of neurons in the brain. According to estimates, the worldwide prevalence of HD ranges from 5 to 10 cases per 100,000 people.CRUC 发表于 2025-3-22 15:54:13
,Role of Exosomes in Parkinson’s and Alzheimer’s Diseases,ears. Exosomes were first thought to be useless cell debris. It has been discovered that exosomes contain a variety of non-coding RNAs, including microRNAs, lncRNAs, and circRNAs, as well as other bioactive compounds. A few of these compounds are functional messenger RNAs (mRNAs), certain proteins,CRUC 发表于 2025-3-22 20:00:12
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,Role of Microbiota-Derived Exosomes in Gut–Brain Communication for the Treatment of Brain Disordersstate of humans. The commensal and pathogenic bacteria both reside in the same environment of the intestinal epithelium, also called the gut-associated lymphoid tissues (GALT) of the host, which strike the balance to maintain the integrity of the intestinal barrier and immune function. On the contraAMOR 发表于 2025-3-23 09:36:56
Advancement of Engineered Exosomes to Deliver Therapeutic Protein Cargos in Brain Disorders,nable early diagnosis, and optimize treatment outcomes. Exosomes can easily penetrate the blood–brain barrier (BBB), provide protection against disease-related molecules, and remain highly stable in peripheral circulation..Exosomes that are released by both active microglia cells and neurons were fo