货物
发表于 2025-3-26 21:27:08
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Infraction
发表于 2025-3-27 02:58:43
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反复拉紧
发表于 2025-3-27 07:28:49
Fine-Tuning the Epigenetic Landscape: Chemical Modulation of Epigenome Editorss toolbox. Here, we provide a comprehensive review of the current state of these cutting-edge systems and specifically discuss their advantages and limitations, offering context to better understand their capabilities.
EXCEL
发表于 2025-3-27 09:43:54
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Minatory
发表于 2025-3-27 15:39:38
Reader-Effectors as Actuators of Epigenome Editing where abnormal and context-specific reader-effectors might impair the effects of epigenome editing. Lastly, we discuss how engineered reader-effectors may complement the epigenome editing toolbox to achieve robust and reliable gene regulation.
obstruct
发表于 2025-3-27 18:25:39
Optimized Protocol for the Regulation of DNA Methylation and Gene Expression Using Modified dCas9-Su 22 amino acids. Moreover, we describe the co-recruitment of TET1 and VP64 for efficient gene activation. Since we showed the manipulation of DNA methylation at specific loci and gene activation, its application could lead to its future use in the clinic.
podiatrist
发表于 2025-3-28 00:25:37
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完全
发表于 2025-3-28 05:56:04
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多余
发表于 2025-3-28 06:32:57
Fluorescent Reporter Systems to Investigate Chromatin Effector Proteins in Living Cellsof regulatory dependencies of the investigated chromatin regulator on endogenous cofactors. The system allows for an easy and dynamic readout at the single-cell level and the ability to compensate for cell-to-cell variances of transcription. The modular design of the system enables the simple adjust
裤子
发表于 2025-3-28 10:34:28
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