BADGE 发表于 2025-3-26 21:18:50
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Diabetes and Pancreatic Cancer: A Bidirectional Relationship Perspective,leading to pancreatic cancer is more in comparison to type 1 diabetes. Successful treatment of obesity and T2DM decreases pancreatic cancer risk. Nevertheless, treatment of T2DM with insulin, insulin analogues, and insulin secretagogues enhances the risk for pancreatic cancer. Metformin, an antidiabConserve 发表于 2025-3-27 15:00:30
Metabolic Adaptations in Diabetes Mellitus and Cancer,CoA derived from fatty acids to fuel citric acid cycle. Cancer cells also present with several metabolic abnormalities where glucose-6-phosphate powers pentose phosphate pathway and contribute ribose required for the rapid proliferation of transformed cells. Cancer cells convert pyruvate to lactate,FAST 发表于 2025-3-27 21:49:26
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Immunotherapy for Diabetogenic Pancreatitis and Pancreatic Cancer: An Update,ally target the insulin-producing pancreatic islets. Pancreatitis is now well-accepted as a fibrotic and inflammatory response. The dawn of immunotherapy has meaningfully enhanced clinical outcomes in various scenarios. However, deficiency in efficient immune checkpoint blockade in a significant pat