Titlebook: Explorations in Aging; Vincent J. Cristofalo,Jay Roberts,Richard C. Adelm Book 1975 The Editor(s) (if applicable) and The Author(s), under

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Aging and the Disposition of Glucose,eny of individual workers in this field has in many cases recapitulated the phylogeny of the entire endeavor. Interest in carbohydrate metabolism and aging dates back well over 50 years. Clinicians became fascinated by a new diagnostic test for diabetes, the glucose tolerance test, and proceeded to

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Alterations in the Growth Rate and Glucose Metabolism of Chinese Hamster Cells in Vitro, of cells undergoing division within the cell population gradually declines (Phase III) and the culture is lost or transforms to a cell line which can be propagated indefinitely. This phenomenon has been described for cell cultures derived from human, mouse, chick, rat kangaroo, rabbit, and tortoise

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The Survival of Haploid and Diploid Vertebrate Cells after Treatment with Mutagens,ates in bacteria, therefore, the proportion of diploid cells which survive mutagen treatment should be at least 10. times that of haploid cells. A haploid-diploid comparison should, in fact, be a test for the mutagenic nature of a compound.

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Gas Chromatographic Analysis of PCBsase in the specific activity of these enzymes during cellular aging (1). Since these enzymes are typically marker enzymes for lysosomes, the findings implied that older cells contained more lysosomes, a conclusion that has since been documented by electron microscopic studies in our lab and by others (2–4).

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https://doi.org/10.1007/978-3-319-89926-8y to respond biochemically to various stimuli (for reviews see Adelman, 1972; Roth and Adelman, 1974; Gusseck, 1972). Many responses of this type directly involve or are mediated by hormones (Roth and Adelman, 1974; Gusseck, 1972).

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Edward S. Kim,Bonnie S. Glissonnted and transferred to new organ culture dishes every 24 hr. The explants were bathed in Eagle’s minimal essential medium with Hanks’ salts and 10% calf serum, supplemented with glutamine and antibiotics.

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Titlebook: Explorations in Aging; Vincent J. Cristofalo,Jay Roberts,Richard C. Adelm Book 1975 The Editor(s) (if applicable) and The Author(s), under

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