沟通
发表于 2025-3-28 15:05:47
Experimental Studies with L-Asparaginase in Mouse Leukemias reversibility of the antileukemic effect of A-ase . and ., the effects of dose and dosage schedule on early and advanced ascitic, subcutaneous, and intracerebral leukemia, and the effect of prior or concomitant treatment with other chemotherapeutic agents on both the half-life of the drug and the i
真实的你
发表于 2025-3-28 21:03:59
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commute
发表于 2025-3-29 00:38:03
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patriarch
发表于 2025-3-29 03:58:40
The Distribution and Clearance of L-Asparaginasecells has been the subject of numerous presentations at this symposium. The purpose of this report is to describe an automated method for the assay of L-asparaginase and to present data concerning the distribution and clearance of administered L-asparaginase.
Magnificent
发表于 2025-3-29 07:27:16
Pharmacokinetic Behavior of L-Asparaginase in Men and in Animalsnt for its characterization, but that as much as possible should be known about its fate in the body — i. e. absorption, blood levels, distribution, elimination, and biotransformation. In the case of Crasnitin . this is of special importance because therapy with enzymes is a rather new field of mode
省略
发表于 2025-3-29 15:27:06
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施魔法
发表于 2025-3-29 16:36:56
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在前面
发表于 2025-3-29 23:36:57
Experimental Studies with L-Asparaginase in Mouse Leukemiasand later as preparations of varying degrees of purity from ., showed it to be a unique agent with a very high chemotherapeutic index which is capable of curing some mouse leukemias and tumors at high doses without assistance from host immune mechanisms. Since the drug also has a similar chemotherap
VEN
发表于 2025-3-30 02:47:46
Experimental Investigations on Problems of the Clinical Use of L-Asparaginaseuseful to study experimentally problems which arose from the clinical use of the enzyme. Consequently we investigated the influence of the following factors on tumor inhibition: dosage, duration of treatment, treatment schedules, treatment of Crasnitin resistant tumors, combined treatment with Crasn
附录
发表于 2025-3-30 06:37:12
Studies on the Glutaminase Activity of E. coli Asparaginase in Tissue Culturee lost the ability to synthesize L-asparagine and thus depend on the exogenous supply of this amino acid. Yet it is not always sufficiently considered that E. coli asparaginase also possesses a small amount of L-glutaminase activity and in high dosage may become effective by depriving the cells