CHYME 发表于 2025-3-30 09:14:05
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T Lymphocytes in EAEalso contribute to pathology. The recovery phase of the disease poses more of a challenge with the potential for various regulatory T cell populations to halt the pathology. We know a good deal about the fine-specificity of T cell recognition of epitopes derived from myelin autoantigens. This, coupl使无效 发表于 2025-3-30 17:59:42
The Role of Complement in EAEt participates in host defence against pathogens by triggering the formation of the membrane attack complex. Complement opsonins (Clq, C3b, iC3b) interact with surface complement receptors to promote phagocytosis while complement anaphylatoxins C3a and C5a initiate local pro-inflammatory responses t大喘气 发表于 2025-3-30 23:00:03
Cytokines in Experimental Autoimmune Encephalomyelitisoinflammatory and anti-inflammatory cytokines and their role in EAE, as shown by expression in nervous tissue, production by cells of the immune and nervous system, experiments with exogenous administration, overexpression, antibody neutralization or knockout mice.救护车 发表于 2025-3-31 01:11:53
The Role of Interferons in Experimental Autoimmune Encephalomyelitiss, functions and applications. We here review studies directed at defining the role played by these molecules when they are produced endogenously or administered exogenously in the course of experimental autoimmune encephalomyelitis (EAE), a model disease considered relevant for the pathogenesis ofheadlong 发表于 2025-3-31 06:08:56
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Free Radicals and Experimental Autoimmune Encephalomyelitis ONOO- species is discussed and the current literature EAE reviewed. The dual nature of free radicals, pathogenic and protective, and the correspondingly conflicting results of therapeutic interventions aimed at diminishing free radicals (in particular reactive nitrogen species), are also discussedSTYX 发表于 2025-3-31 16:56:09
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https://doi.org/10.1007/978-3-642-49903-6ific for myelin-associated autoantigens of the central nervous system (CNS). This chapter presents an overview of some useful strategies and protocols by which EAE can be induced, and discusses the pros and cons of various approaches.AMEND 发表于 2025-3-31 23:30:50
Book 2005 the different experimental models for MS (including immune-mediated and viral) under one roof, and highlights aspects that are different or shared among these experimental models. It’s aim is to improve our understanding of this devastating disease and help us think about potential additional therapies for it..