FLIT
发表于 2025-3-28 15:27:42
Hepatocarcinogensociated more directly with the development of these tumors in man. Among them are: aflatoxins, cycasin, vinyl chloride, and estrogens, agents of quite different chemical nature. In experimental animals, mostly the rat and the mouse, quite a number of diverse chemicals have been demonstrated to produ
SPURN
发表于 2025-3-28 21:46:00
The Induction of Localized Tumours by Carcinogens Implanted into the Liver process of fibrogenesis and scarring in the liver — the result of toxic injury caused by the rather large doses of hepatocarcinogens then used — from the phenomenon of hepatocarcinogenesis proper. It was assumed that the implantation of known hepatocarcinogens into the liver would lead only to a gr
Provenance
发表于 2025-3-29 01:08:57
Two Stage Theory of Carcinogenesis: A Critical Review Introducing the Concept of Modulationt event which introduces the tissue or some of its cells into that process. That event may be a physical (radiation) or a chemical mostly mutagenic treatment but also a viral infection or even a transfection of a piece of viral DNA (Lacey et al.1986). In most experimental protocols reported so far f
Expurgate
发表于 2025-3-29 05:10:16
Modulating Factors of Hepatocarcinogenesis, the carcinogenic process can either evolve naturally or operationally be modulated. The factors that modulate an initiated carcinogenesis can have positive or negative effects. When the incidence and/ or the yield of cancer is increased and/or the latency period is decreased by the modulating trea
形上升才刺激
发表于 2025-3-29 07:34:43
Sex Hormones as Modulators of Liver Tumor Developmentty (2), enzymatic competence of tissue(s) to activate the procarcinogen (3–5), the interaction of ultimate carcinogenic moiety with specific macromolecular site(s) (6,7), the rate of removal of the formed adduct(s) (8), the degree of macromolecular repair (9,10), caloric intake (11–13), immune compe
STANT
发表于 2025-3-29 14:25:04
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conquer
发表于 2025-3-29 18:17:05
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原始
发表于 2025-3-29 23:17:30
Cellular Differentiation During Neoplastic Development in the Liverormal counterparts. Thus, hepatocellular, cholangiocellular and diverse mesenchymal tumors are distinguished. This histogenetic classification was established by light microscopy. It has been supported by many electron microscopical results and more recently also by immunohistochemical investigation