窗帘等 发表于 2025-3-25 03:57:29
http://reply.papertrans.cn/32/3185/318415/318415_21.pngcreditor 发表于 2025-3-25 09:32:23
Metabotropic Glutamate Receptors and Neurodegenerationential application of mGlu5 receptor antagonists in chronic neurodegenerative disorders, such as Amyotrophic Lateral Sclerosis (ALS) and Alzheimer’s disease (AD). MGlu2/3 receptor agonists inhibit glutamate release, and also promote the synthesis and release of neurotrophic factors in astrocytes. Th含糊其辞 发表于 2025-3-25 15:12:02
Mechanisms of Excitotoxicity and Excitoprotection such as caspase-3. Essentially all subcellular compartments, including the endoplasmic reticulum, mitochondria and nucleus are involved in the excitotoxic process. Excitotoxic cascades are initiated in postsynaptic dendrites where glutamate receptors are most highly concentrated, and may either cau多嘴 发表于 2025-3-25 17:18:12
http://reply.papertrans.cn/32/3185/318415/318415_24.png地牢 发表于 2025-3-25 21:36:49
http://reply.papertrans.cn/32/3185/318415/318415_25.pngcertain 发表于 2025-3-26 02:54:57
http://reply.papertrans.cn/32/3185/318415/318415_26.png无孔 发表于 2025-3-26 07:36:29
Glutamate Transmission in the Pathogenesis of Parkinson’s Diseasenuclein and parkin. Moreover, compelling evidence supports the involvement of mitochondrial metabolism failure as an essential cofactor in the pathogenesis of PD. Interestingly, some environmental toxins are thought to be able to act as mitochondrial toxins. The comprehension of the pathways leadingOintment 发表于 2025-3-26 10:45:44
http://reply.papertrans.cn/32/3185/318415/318415_28.png门窗的侧柱 发表于 2025-3-26 15:07:29
Hermann Lang,Stefan Schilling,Hermann Faller a local and parenchimal inflammatory reaction characterised by astroglia and microglia activation has been reported in several brain pathologies including prion diseases and various dementias like Alzheimer’s disease and the AIDS dementia complex. In agreement, stimulation of the calcium-dependentatrophy 发表于 2025-3-26 20:39:58
http://reply.papertrans.cn/32/3185/318415/318415_30.png