暗讽 发表于 2025-3-28 16:13:59
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Role of Cilia and Left-Right Patterning in Congenital Heart Diseaseng congenital heart disease. This is supported by human clinical studies, which showed a high prevalence of ciliary dysfunction and respiratory symptoms and disease in patients with congenital heart disease. Our mouse studies indicate this involves essential roles for both primary and motile cilia iAcumen 发表于 2025-3-29 12:29:20
Pulmonary Arterial Hypertension in Patients with Heterotaxy/Polysplenia Syndromesystemic-to-pulmonary shunt. However, its etiology is uncertain and its management is not well established. There was only a Japanese report about PAH in consecutive patients with heterotaxy/polysplenia syndrome . They seemed to develop pulmonary vascular obstructive disease earlier and more seveFLOUR 发表于 2025-3-29 19:38:42
http://reply.papertrans.cn/32/3164/316390/316390_47.pngFunctional 发表于 2025-3-29 22:41:07
Meis1 Regulates Postnatal Cardiomyocyte Cell Cycle Arrest1078–1080, 2011; Proc Natl Acad Sci U S A 110:187–92, 2013). However, this regenerative capacity is lost by postnatal day 7 and the mechanisms of cardiomyocyte cell cycle arrest remain unclear. The homeodomain transcription factor Meis1 is required for normal cardiac development but its role in card得意牛 发表于 2025-3-30 02:21:04
Intercellular Signaling in Cardiac Development and Disease: The NOTCH pathwayr cardiac development may cause congenital heart disease (CHD), manifested in the newborn or in the adult. Notch is an ancient, highly conserved signaling pathway that communicates adjacent cells to regulate cell fate specification, differentiation, and tissue patterning. Mutations in Notch signalincertitude 发表于 2025-3-30 04:41:57
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