GLEAN
发表于 2025-3-30 08:11:45
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diabetes
发表于 2025-3-30 16:24:47
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Devastate
发表于 2025-3-30 20:00:15
Ryan Holmes,Darren McCauley,Nick HanleyG1478 and monensin causes endosome-associated EGFR activation. Phosphorylated surface EGFR levels are undetectable during the treatment. This is a unique and novel approach to study endosomal signaling and its physiological relevance. The protocol is transferable to study endosomal signaling of other receptor tyrosine kinases.
犬儒主义者
发表于 2025-3-30 21:05:00
Methods to Investigate EGFR Ubiquitinationd reliable method to assess EGFR ubiquitination from low amount of sample; lastly, we illustrate an immunofluorescence protocol to visualize ubiquitinated species (including the EGFR itself) within the EGFR-positive endocytic compartments upon EGF stimulation.
liposuction
发表于 2025-3-31 04:49:09
Activation of Endosome-Associated Inert EGF Receptor Following InternalizationG1478 and monensin causes endosome-associated EGFR activation. Phosphorylated surface EGFR levels are undetectable during the treatment. This is a unique and novel approach to study endosomal signaling and its physiological relevance. The protocol is transferable to study endosomal signaling of other receptor tyrosine kinases.