DOSE 发表于 2025-3-25 05:51:44
http://reply.papertrans.cn/32/3127/312635/312635_21.pnginsert 发表于 2025-3-25 10:51:50
https://doi.org/10.1007/978-3-658-28791-7fferentially methylated regions been elaborated. These regions encompass genes that in some cases interact with longevity and disease-associated genes. Histone modifications have now become of interest in aging studies. Model organisms have provided substantial evidence that some of the enzymes that条约 发表于 2025-3-25 15:24:39
Über das Problem Hartbrand - Weichbrandific community has begun the process of associating heritable SNPs with genetic predispositions for disease. However, models for how the environment interacts with the static DNA code are now needed. The exciting new field of epigenetics allows for a newer perspective of how a cell’s DNA sequence dyContend 发表于 2025-3-25 18:16:11
https://doi.org/10.1007/978-3-663-07337-6e possible to describe disease mechanisms, discover novel genetic variants associated with disease, better understand heterogeneity between populations, identify populations with higher risk from exposure, and target preventive and therapeutic interventions. However, there are several challenges toAPEX 发表于 2025-3-25 23:00:27
https://doi.org/10.1007/978-3-663-20343-8ntial human carcinogens have been expanded to include those that do not appear to damage DNA directly but rather alter gene expression patterns through epigenetic mechanisms such as alterations in DNA methylation, histone modifications/chromatin alterations, and microRNA. Given that almost 25 % of a补充 发表于 2025-3-26 04:10:22
Wolfgang Krönert,Gerhard Rehfeldn observed in multiple cell types, such as, B-cell and T-cell lymphocytes, and non-mammalian organisms, such as ciliates. These genome restructuring processes are driven by epigenetic markings, including DNA methylation status, histone modification, and/or noncoding RNA transcription, which are modi雪上轻舟飞过 发表于 2025-3-26 06:33:12
https://doi.org/10.1007/978-3-642-50806-6to pathogens, define how the body responds to stimuli and the susceptibility to complex diseases like asthma, obesity, cardiovascular disease, and cancer. This chapter summarizes the relationship between the environment, epigenetics and disease. In the last 20 years, this relationship has been the f设施 发表于 2025-3-26 09:41:07
http://reply.papertrans.cn/32/3127/312635/312635_28.pngLipoprotein 发表于 2025-3-26 15:54:41
Molecular and Integrative Toxicologyhttp://image.papertrans.cn/e/image/312635.jpg抗原 发表于 2025-3-26 18:58:27
https://doi.org/10.1007/978-1-4471-6678-8Environmental toxicants; Epigenetic modulations; Measuring epigenetics; Pregnancy exposures; epidemiolog