合群
发表于 2025-3-26 20:56:38
Handbook of Experimental Pharmacologyhttp://image.papertrans.cn/e/image/309817.jpg
灌溉
发表于 2025-3-27 03:01:44
https://doi.org/10.1007/978-3-540-89042-3meable to Ca. and Na. and activated by the second messenger NAADP as well as the phosphoinositide, PI(3,5)P. and/or voltage. Here, we review the proteins that interact with these channels including recently identified NAADP receptors.
aptitude
发表于 2025-3-27 08:03:38
Endo-Lysosomal Two-Pore Channels and Their Protein Partnersmeable to Ca. and Na. and activated by the second messenger NAADP as well as the phosphoinositide, PI(3,5)P. and/or voltage. Here, we review the proteins that interact with these channels including recently identified NAADP receptors.
Inkling
发表于 2025-3-27 13:27:09
NAADP-Mediated Ca2+ Signallingto our understanding of Ca. signalling, not least in providing a link between cell stimulation and Ca. release from lysosomes and other acidic Ca. storage organelles. In addition, the hallmark concentration-response relationship of NAADP-mediated Ca. release, shaped by striking activation/desensitiz
杂色
发表于 2025-3-27 14:31:49
NAADP-Dependent TPC Currentlian cells. These channels have been implicated in Ca. signaling initiated from the endolysosomes, vesicular trafficking, cellular metabolism, macropinocytosis, and viral infection. Although TPCs have been shown to mediate Ca. release from acidic organelles in response to NAADP (nicotinic acid adeni
beta-cells
发表于 2025-3-27 20:42:22
NAADP-Evoked Ca2+ Signaling: The DUOX2–HN1L/JPT2–Ryanodine Receptor 1 Axislism and Ca. mobilizing activity of NAADP are reviewed, with emphasis on a novel redox cycle between the inactive reduced form, NAADPH, and the active oxidized form, NAADP. Oxidation from NAADPH to NAADP is catalyzed in cell free system by (dual) NADPH oxidases NOX5, DUOX1, and DUOX2, whereas reduct
cathartic
发表于 2025-3-27 22:34:05
TPC Functions in the Immune System In this chapter, we focus on their function in immune cells and immune reactions. Therefore, we first give an overview of the cellular immune response and the partaking immune cells. Second, we concentrate on ion channels which in the past have been shown to play an important role in the regulation
LANCE
发表于 2025-3-28 03:07:28
Lysosomal Ion Channels and Lysosome–Organelle Interactionstes (MCSs) with ER and mitochondria, lysosomes mediate bidirectional transport of metabolites and ions between lysosomes and organelles that regulate lysosomal physiology, movement, membrane remodeling, and membrane repair. In this chapter, we will first summarize the current knowledge of lysosomal
carbohydrate
发表于 2025-3-28 08:42:31
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间接
发表于 2025-3-28 13:03:41
Lysosomal Potassium Channelsmitophagy, and autophagy. To function properly, intralysosomal environments are strictly controlled by a set of integral membrane proteins such as ion channels and transporters. Potassium ion (K.) channels are a large and diverse family of membrane proteins that control K. flux across both the plasm