Herpetologist
发表于 2025-3-26 21:00:46
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恶臭
发表于 2025-3-27 03:47:14
The Natural History of ADP-Ribosyltransferases and the ADP-Ribosylation System,h was acquired prior to the last eukaryotic common ancestor. They were incorporated into eukaryotic regulatory/epigenetic control systems (e.g., PARP family and NEURL4), and also used as defensive (e.g., pierisin and CARP-1 families) or immunity-related proteins (e.g., .-like ARTs). The ADP-ribosyla
ERUPT
发表于 2025-3-27 06:11:35
Identification and Analysis of ADP-Ribosylated Proteins,d either by IMAC (using the affinity of the pyrophosphate group for heavy metal ions) or by immobilized boronic acid beads (using the affinity of the vicinal ribose hydroxy groups for boronic acid). The identification of the modified peptides usually requires tandem mass spectrometric measurements.
庇护
发表于 2025-3-27 12:42:34
Regulation of Nitrogenase by Reversible Mono-ADP-Ribosylation,ring nitrogenase activity. DraT and DraG activities are reversibly regulated through interaction with P. signaling proteins. Bioinformatics analysis showed that DraT homologs are restricted to a few nitrogen-fixing bacteria while DraG homologs are widespread in Nature. Structural comparisons indicat
comely
发表于 2025-3-27 15:49:19
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破裂
发表于 2025-3-27 20:04:40
Pierisins and CARP-1: ADP-Ribosylation of DNA by ARTCs in Butterflies and Shellfish,tterfly is suggested to be a defense factor against parasitization by wasps. Other type of DNA ADP-ribosyltransferase is present in certain kinds of edible clams. For example, the CARP-1 protein found in . consists of an enzymatic domain without a possible receptor-binding domain. Pierisin and CARP-
CHART
发表于 2025-3-27 22:32:55
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和谐
发表于 2025-3-28 05:58:27
0070-217X en by leading experts in the field.Includes supplementary ma.This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections:.· Evolution and detection of endogenous ADP-ribosyla
高尔夫
发表于 2025-3-28 09:00:03
https://doi.org/10.1007/978-3-642-50227-9e of these enzymes in complex with a substrate protein. Recently, the structures of two such complexes became available, which shed new light on the mechanisms of mono-ADP-ribosylation. In this review, we consider the reaction mechanism based on the structures of ADP-ribosyltransferases in complex with a substrate protein.
menopause
发表于 2025-3-28 14:01:41
https://doi.org/10.1007/978-3-319-01053-3are beginning to be defined. Reader domains that specifically recognize mono-ADP-ribosylated target proteins and erasers that remove the mono-ADP-ribosyl mark have been identified. Here, we review the contribution of crystal structures to our understanding of the putative mono-ADP-ribosyltransferases with Diphtheria toxin and ARTD1/PARP1 homology.