伤心 发表于 2025-3-30 09:58:24
Function and Regulation of Mitochondrial Voltage-Dependent Anion Channelnel is responsible for most of the metabolite flux in and out of mitochondria. Small ions, adenine nucleotides such as ATP and ADP, and other water soluble mitochondrial respiratory substrates cross the MOM through VDAC. Therefore, any restriction to metabolite exchange through VDAC is able to leadFacilities 发表于 2025-3-30 14:57:45
http://reply.papertrans.cn/31/3066/306524/306524_52.pngcanvass 发表于 2025-3-30 19:28:10
http://reply.papertrans.cn/31/3066/306524/306524_53.png无法解释 发表于 2025-3-30 21:04:40
http://reply.papertrans.cn/31/3066/306524/306524_54.png因无茶而冷淡 发表于 2025-3-31 01:32:48
Viroporins and compartment, including endocytic/exocytic vesicles, ER, mitochondria, Golgi, and the plasma membrane. Viroporins are generally very small (<100 amino acids) integral membrane proteins that share common structure motifs (conserved cluster of basic residues adjacent to an amphipathic alpha-helix)侵害 发表于 2025-3-31 05:23:39
Pore-Forming Colicins: Unusual Ion Channels – Unusually Regulatedthe plasmid bearing cells have an immunity protein that protects them from their own specific colicin. Colicins kill by peptidoglycan synthesis inhibition, nuclease digestion or pore formation. This review describes how the pore-forming colicins function, with reference to other types as needed. TheTexture 发表于 2025-3-31 12:27:07
Anthrax Toxin Protective Antigen Forms an Unusual Channel That Unfolds and Translocates Proteins Acratal, the agent has been weaponized for biowarfare and bioterrorism. Anthrax toxin is comprised of three individually nontoxic proteins, protective antigen (PA), lethal factor (LF), and edema factor (EF). But, to physiologically function, these individual subunits assemble into potent cytotoxins con懦夫 发表于 2025-3-31 14:12:18
Staphylococcal β-barrel Pore-Forming Toxins: Mushrooms That Breach the Greasy Barrierthe physical and chemical gradients across the membrane of the targeted cell by generating well-defined transmembrane pores, ultimately causing the cell death. Such a form of biomolecular attack is a ubiquitous membrane-perforation mechanism in numerous organisms, including bacterial systems and euk