Surgeon
发表于 2025-3-27 00:04:20
Neuroprotective Treatment in Primary Progressive Multiple Sclerosis: a Phase I/II Study with Riluzois might be explained by observations, especially from magnetic resonance imaging (MRI) studies, that the correlation of inflammation with disease progression and development of disability is poor .
水獭
发表于 2025-3-27 05:00:48
Early Treatment of Progression in Multiple Sclerosis,at axonal damage occurs early during RRMS. Disease progression thus develops well in advance of clinical progression and remains subclinical because, due to compensatory mechanisms, impairment does not interfere with daily living activities at that stage.
Clinch
发表于 2025-3-27 05:33:19
Soluble VCAM-1 Release Indicates Inflammatory Blood-Brain Barrier Pathology and Further Modulates Ain barrier (BBB) during inflammatory central nervous system (CNS) diseases . Adhesion molecules can be induced by proinflammatory cytokines, like tumor necrosis factor-a (TNF-α), on various cell types, e.g., endothelial cells, macrophages, and lymphocytes .
Aspiration
发表于 2025-3-27 11:06:31
gen for autoreactive antibodies might be the central nervous system (CNS) specific myelin oligodendrocyte glycoprotein (MOG), which is exclusively localized on the surface of myelin sheaths and oligodendrocytes.
贪婪地吃
发表于 2025-3-27 17:20:17
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滋养
发表于 2025-3-27 19:24:53
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过分自信
发表于 2025-3-27 22:30:33
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巧思
发表于 2025-3-28 03:30:48
Inflammation, Demyelination, and Axonal Degeneration: Three Aspects of the Pathogenesis of Multiple relapse, for instance, or the transition from relapsing-remitting disease to progressive accumulation of disability. Here, we report observation from the close study of a small number of patients treated with an experimental agent, Campath-1H, that cast some light on these issues.
Fortuitous
发表于 2025-3-28 07:28:36
Genetic Regulation of Nerve Cell Death/Glial Activation and Protective Effects of Myelin Basic Prot to ten genes theoretically having a major impact on disease susceptibility . This is supported by epidemiological data demonstrating a considerable lowering of concordance rates from monozygotic to dizygotic twins . It has been known for approximately 30 years that certain haplotypes of the
改良
发表于 2025-3-28 14:30:35
Neuroprotective Treatment in Primary Progressive Multiple Sclerosis: a Phase I/II Study with Riluzoomponent of the disease. Their main clinical impact is on relapses whereas an effect on permanent disability so far has been less well established. This might be explained by observations, especially from magnetic resonance imaging (MRI) studies, that the correlation of inflammation with disease pro