Addiction
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锯齿状
发表于 2025-3-21 23:46:37
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lipids
发表于 2025-3-22 02:57:05
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火花
发表于 2025-3-22 07:52:35
Epidermal Growth Factor Receptor Expression in Head and Neck Tumorigenesis and Saturation of EGFR wrials is the understanding that the whole epithelial lining of the tract shares a common carcinogenic exposure, resulting in an increased cancer risk throughout the exposed epithelum. This entire epithelium was first described as “condemned mucosa” associated with “field cancerization” by Slaughter
RADE
发表于 2025-3-22 10:44:47
The Role of Estrogen in the Regulation of EGFR Expression,987). Moreover, many cell regulators such as EGF, 12-O-tetradecanoyl phorbol acetate (TPA), and sodium butyrate have opposite effects on the expression of the two receptors (Lee et al. 1989; Secada et al. 1991; De Fazio et al. 1992). This well-established inverse correlation between EGFR and ER expr
Magnitude
发表于 2025-3-22 15:16:41
Conference proceedings 1997poptosis, cell migration, and cell shape. Activation of autocrine growth loops, consisting in solid human tumors of upregulated expression of EGFR together with increased production of ligands suggested its crucial role in autonomous tumor growth.
Magnitude
发表于 2025-3-22 17:38:00
0947-6075 tiation, apoptosis, cell migration, and cell shape. Activation of autocrine growth loops, consisting in solid human tumors of upregulated expression of EGFR together with increased production of ligands suggested its crucial role in autonomous tumor growth.978-3-662-03393-7978-3-662-03391-3Series ISSN 0947-6075
Hectic
发表于 2025-3-22 23:40:52
Michal Borkovec,Ger J. M. Koperts with transgenic mice suggest that an autocrine mechanism involving the EGFR could be expected to play a role in the initiation and/or progression of tumors. Transgenic mice expressing transforming growth factor-α (TGF-α) were reported to develop mammary and hepatocellular carcinoma as well as pan
magnanimity
发表于 2025-3-23 03:22:12
ptide substrate and the ATP binding sites. In the phosphorylated form it is expected to become disengaged from the active center and to allow access of the substrates. In terms of homology it is possible that such a mechanism might operate similarly in other RTK. (2) Autophosphorylation creates bind
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发表于 2025-3-23 09:17:48
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