向外 发表于 2025-3-27 00:51:44
GABA Antagonists,al role at particular synapses in the nervous system. They are to reduce its availability and release through a presynaptic action or to reduce its effects with appropriate postsynaptic antagonists. The former might be achieved by specifically destroying GABA-containing neurons, inhibiting its synthPRISE 发表于 2025-3-27 02:55:41
Specificity of Drugs as Tools in Psychopharmacology,the dopaminegic system is utilized to establish whether another drug exerts its pharmacological effects via that monoammergic system. .-Amphetamme is believed to act on the dopaminergic system because some, but not all, pharmacological effects are inhibited by antidopammergic agents流出 发表于 2025-3-27 07:53:47
Determination of Monoamine Turnover by Blockade of Their Synthesis or Metabolism,ed and destroyed at various rates, yet their content in neuronal tissue remains relatively constant. Thus, it is not possible to evaluate neuronal function solely from the content of the transmitter in a tissue. A better estimate of neuron function can be obtained from the rate of formation of the aMorphine 发表于 2025-3-27 12:58:59
Dopamine Receptors and Neuroleptic Drugs,only essential tools in neuropharmacology, but are also guides that neurobiologists follow to identify, isolate, and even dismantle the molecular structure of brain neuroreceptors. For many people, it is not clear why potent neurotransmitter antagonists are an absolute requirement for these studies法律的瑕疵 发表于 2025-3-27 16:49:11
Use of 5-HT Receptor Agonists and Antagonists for the Characterization of Their Respective Receptorted in 1948. The compound gained wide interest among pharmacologists, and in a short time a great number of in vitro and in vivo pharmacological tests had been developed, and a variety of drugs interacting with the actions of serotonin were rapidly discovered. In 1966, Gyermek, in a review on “DrugsExternalize 发表于 2025-3-27 20:28:49
http://reply.papertrans.cn/29/2833/283215/283215_36.png存在主义 发表于 2025-3-28 01:17:45
Drug-Induced Behavioral Models of Central Disorders,f models that highlight their usefulness and limitations. I have made my choice of models to discuss partly on the basis of their role (putative or actual) in modeling diseases, partly on their heuristic value in stimulating research, and partly because of my own personal interests. Some diseases wi羽毛长成 发表于 2025-3-28 02:55:25
Determination of Acetylcholine Dynamics,line (ACh) and choline stored in neurons by injecting labeled precursors of ACh, and by measuring simultaneously the changes with time in the specific activities of choline and ACh (Cheney et al., 1974, 1975a; Costa et al. 1975; Dross and Kewitz, 1966; Hanin et al., 1973; Jenden et al., 1974; Racagn捐助 发表于 2025-3-28 08:42:45
GABA Antagonists,d to destroy (lyse) synaptosomes containing GABA in vitro (Docherty et al., 1983), the method is not applicable in vivo. Intracerebral injection of tetanus toxin has been shown to reduce GABA-mediated inhibition by reducing release of the transmitter (Collingridge and Davies, 1982), but this toxin h束缚 发表于 2025-3-28 12:17:56
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