Daily-Value
发表于 2025-3-28 15:39:47
Strong, Em, and Other Phrase Elementstion sites of various proteins, such as the λ-repressor/O. complex (.), RNA polymerase-.P1 promoter of . (.), RNA polymerase/cyclic AMP receptor protein (CRP)-.P2 promoter of . (.), CRP/CytR repressor-.P2 promoter of . (.), and transcription factor IIIA/. 5s internal control region (.).
阐释
发表于 2025-3-28 19:49:29
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健谈的人
发表于 2025-3-29 02:48:05
Strong, Em, and Other Phrase Elementsat effort over many years to establish where on the DNA these drugs interact, with the expectation that a good understanding of the nature of the DNA receptor site would lead to the design of a new generation of these drugs.
使害羞
发表于 2025-3-29 06:39:39
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广口瓶
发表于 2025-3-29 09:47:40
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态学
发表于 2025-3-29 11:26:36
ently available calorimeters can be used at concentrations approaching levels used in UV-visible studies (.–.). Combination of the calorimetric measurements with an analysis of the corresponding binding isotherm can provide both the enthalpy and entropy changes (ΔG = ΔH - TΔS) for attaching a drug to a DNA lattice site (.–.,.).
数量
发表于 2025-3-29 16:29:56
,DNA Polymerase Inhibition Assay (PIA) for the Detection of Drug–DNA Interactions,lators and nonintercalative binding agents, such as netropsin (unpublished results). This method is relatively safe for the user, as it employs less radioisotope than is required for the detection of alkylation products by conventional postlabeling or Maxam and Gilbert chemical cleavage techniques.
expansive
发表于 2025-3-29 20:44:57
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Hectic
发表于 2025-3-30 02:56:10
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duplicate
发表于 2025-3-30 05:58:33
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