acheon 发表于 2025-3-28 16:41:16
https://doi.org/10.1007/978-94-017-1149-4 the choice is determined by the clinical pattern of the drug eruption and its underlying mechanism. Skin prick tests and intradermal tests with immediate readings are indicated for urticaria and anaphylactic reactions, whereas patch test and intradermal tests with late readings are useful for delay健忘症 发表于 2025-3-28 18:54:49
Byelorussian Soviet Socialist Republic,ophil activation test, T cell drug-induced cytokine release, lymphocyte proliferation or surface marker change detection. Variable sensitivity of . tests is the main barrier in wider utilisation, in addition to need for specialist equipment and technical expertise. Increasingly, . testing is performAWRY 发表于 2025-3-29 02:43:34
https://doi.org/10.1007/978-94-017-1149-4hin 24 h of ingesting a drug, and less than 1 h if the individual is pre-sensitised with specific IgE against the culprit (allergic urticaria: type I hypersensitivity). The drug in question is usually easy to identify given the short latency period between drug exposure and development of urticaria.地名词典 发表于 2025-3-29 03:38:49
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https://doi.org/10.1007/978-94-017-1149-4 The two entities represent either end of a severity spectrum with SJS at the milder end (<10% body surface area epidermal detachment) and TEN at the severe end (>30% epidermal detachment). During the acute phase, SJS/TEN is associated with multiple morbidities and a high mortality (15–30%). There aharangue 发表于 2025-3-29 14:58:41
Byelorussian Soviet Socialist Republic,ory pathway resulting in the accumulation of neutrophils in the epidermis. Clinical and histopathological similarities between AGEP and generalised pustular psoriasis (GPP) are mirrored in shared pathogenetic processes. Genetic studies have identified mutations in the . gene in both GPP and AGEP. .hazard 发表于 2025-3-29 17:22:24
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Byelorussian Soviet Socialist Republic,nicians face further difficulties in the wide range of drug causes and long latency period of exposure before rash appears. Novel drugs such as biologics and immune checkpoint inhibitors are now increasingly implicated and pose new clinical challenges.chance 发表于 2025-3-30 02:47:36
https://doi.org/10.1007/978-94-017-1149-4ulprit agents. Skin rashes are less common in drug-induced systemic LE (SLE) than in idiopathic SLE with a low incidence of malar rash, discoid lesions, alopecia and photosensitivity. However, drug-induced subacute cutaneous lupus erythematosus (SCLE) is clinically similar to the idiopathic form of匍匐前进 发表于 2025-3-30 08:03:34
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