Halcyon 发表于 2025-3-21 16:25:01
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Janette L. Dunn,Ian D. Hands,Colin A. Bates hyperlipidemia that effectively and safely lowers cholesterol through competitive inhibition of HMG-CoA reductase. This chapter discusses the four major factors that contributed to this breakthrough discovery: (1) the uniqueness of the discovery program, (2) the adoption of a highly efficient reseaTremor 发表于 2025-3-22 02:56:39
The Dynamic Jahn-Teller Effect in Cu(II)/MgO during its development process. Pravastatin became the second statin in the world in terms of commercialization (1989). Although the launch of pravastatin was delayed, it demonstrated hydrophilicity and organ selectivity unlike lovastatin and simvastatin, which enabled its global success. Indeed, i不可思议 发表于 2025-3-22 07:20:05
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Vitalism Versus Emergent Materialismi Pharmaceutical. Both are excellent antimicrobials with wide antibacterial spectrums, and levofloxacin is the world’s first optically active fluoroquinolone. Daiichi Pharmaceutical conducted research and development (R&D) over approximately 20 years to discover and develop these two drugs. The R&DVEIL 发表于 2025-3-22 21:06:43
Sebastian Normandin,Charles T. Wolfe It works by blocking adrenergic α.-adrenoceptors. Dysuria covers a variety of urogenital issues, including prostatic hyperplasia, polyuria, and urinary incontinence. Among these conditions, tamsulosin is effective at reducing dysuria caused by hypertrophy of the prostatic gland. Tamsulosin is prescCampaign 发表于 2025-3-22 21:26:11
https://doi.org/10.1007/978-94-007-2771-7ion of pranlukast is summarized by its provision of an oral agent with high efficacy against bronchial asthma, and its novel mechanism of action. The case of pranlukast development has the following implications. The first is the importance of the contribution of the underlying scientific knowledgeFUME 发表于 2025-3-23 03:07:44
Pollutant Dispersion in an Urban Areaf transplantation medicine and autoimmune diseases and has had a significant impact on patients. It also generated large sales for Fujisawa as a blockbuster drug. The notable aspect of the discovery and development process of tacrolimus are as follows. First, no compound with immunosuppressive functFilibuster 发表于 2025-3-23 06:18:07
Ecology and Adaptive Strategies,sed for the treatment of Type 2 diabetes, and acts by lowering blood glucose levels. The thiazolidinedione backbone discovered by Takeda Pharmaceutical was widely adopted in industry. Research on pioglitazone began as a result of serendipitous discovery of its lead compound during research on lipid-