heterogeneous 发表于 2025-3-28 15:28:03
Absolute and Relative Bioavailability,pect for the pharmaceutical agency. The achievement of this target gives positive economic benefits as reducing drug dosage and medical impacts in decreasing toxicity and bacterial resistance in case of antimicrobials. Various factors may reduce the availability of drugs. There are numerous ways tomyocardium 发表于 2025-3-28 19:45:13
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Chronopharmacology in Drug Development, as well in the peripheral tissues has been convincingly demonstrated to be circadian phase dependent for many genes. In addition, seasonal gene expression – with inverse rhythms in the Northern and Southern Hemisphere – has been evidenced as well. Taking into account these rhythmic changes in the bhomeostasis 发表于 2025-3-29 07:22:19
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Clinical Pharmacology of Tinnitus: Design and Evaluation,t an attractive target for pharmacotherapy. However, none of the so far conducted clinical trials with the use of pharmacological substances could be called a thrilling success. There are multiple reasons for this, which are discussed in this chapter. Moreover, a comprehensive overview of factors thAbominate 发表于 2025-3-29 16:35:29
Clinical Quality Management System,e updates of the Guidelines and especially its Addendum that in Europe became effective in 2017 have not fundamentally changed the content of this Guideline but introduced technology and approaches that were unknown when the GCP Guideline got issued for the first time. Twenty years ago锡箔纸 发表于 2025-3-29 22:54:30
Clinical Studies in Geriatric Population,ps. When considering the demographic change in most industrialized countries and the fact that seniors receive the highest share of all drugs, a need for clinical trials with elderly patients is obvious. Potential pharmacokinetic as well as pharmacodynamic changes in comparison to younger adults hav准则 发表于 2025-3-30 01:35:09
Clinical Studies in Infants (Pediatric Pharmacology),ildren to administer medicines outside their market authorization. Even if authorized, pediatric medicines may not be age-appropriate for a broad range of therapeutic areas. This has been recognized as very unsatisfactory by all stakeholders involved and makes clinical pharmacological studies in chi要素 发表于 2025-3-30 06:52:48
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