Consequence
发表于 2025-3-28 17:58:44
Müfit Bahadir,Harun Parlar,Michael Spitellern with unique cell surface determinants was confined largely to immunology groups (Mason and Williams, 1980). As clinical applications appear practical these systems are likely to come increasingly under the purview of pharmacologists. The point of view of this paper is that the questions and tools
马笼头
发表于 2025-3-28 19:30:50
Müfit Bahadir,Harun Parlar,Michael Spitellerry the drug is attached to or associated with a ligand which recognizes a specific receptor on the surface of a target cell. The ligand can be a component of a phospholipid vesicle, e.g. liposome, a lipoprotein particle or a chemical derivative of a macromolecule, small peptide or oligosaccharide (F
放气
发表于 2025-3-29 02:43:04
Müfit Bahadir,Harun Parlar,Michael Spitellern. The concept is not new since compounds such as acetylsalicylic acid (aspirin), as a prodrug of salicylic acid, and methenamine, as a prodrug of formaldehyde, were discovered in the late 19th century. The term “pro-drug or “pro-agent” was first used by Albert (1958) who suggested that this approac
backdrop
发表于 2025-3-29 05:31:43
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MEN
发表于 2025-3-29 09:48:20
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innate
发表于 2025-3-29 12:11:19
Pharmacodynamic Considerations in the Development of New Drug Delivery Concepts correlations that have been defined, it is important to realize that the relationships are only meaningful at steady state or at a time when the ratio of the drug concentrations at the site of action and in plasma can be expected to remain constant over time; that is, during the terminal log-linear
Expand
发表于 2025-3-29 18:41:27
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cardiovascular
发表于 2025-3-29 19:43:39
Ronald T. Borchardt,Arnold J. Repta,Valentino J. S
Microaneurysm
发表于 2025-3-30 02:02:21
A survey of the experimental situation, correlations that have been defined, it is important to realize that the relationships are only meaningful at steady state or at a time when the ratio of the drug concentrations at the site of action and in plasma can be expected to remain constant over time; that is, during the terminal log-linear
Anthology
发表于 2025-3-30 04:17:20
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