Motilin 发表于 2025-3-26 21:48:27
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Guiding Medicinal Chemistry with Fragment Molecular Orbital (FMO) Method,its strength in kcal/mol and chemical nature: hydrophobic, electrostatic, etc) that would otherwise be hard to detect. In this chapter, we describe the FMO method and illustrate its application in the discovery of the benzothiazole (BZT) series as novel tyrosine kinase ITK inhibitors for treatment of allergic asthma.EWE 发表于 2025-3-27 05:28:17
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