负担 发表于 2025-3-28 17:19:14
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https://doi.org/10.1007/978-3-319-44019-4g different missing data mechanisms for incomplete responses in short-term and longitudinal studies, as well as for missing covariates. We critically discuss common ad hoc strategies for dealing with incomplete data, such as complete-case analyses and naive methods of imputation, and we review more机密 发表于 2025-3-29 04:26:19
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Mindfulness in Behavioral Healthe same treatment or sets of combinations of treatments. An efficient solution to determine which intervention is most promising are multi-arm multi-stage clinical studies (MAMS). In this chapter we will discuss the general concept to designing MAMS studies within the group sequential framework and pLigneous 发表于 2025-3-29 12:17:10
Handbook of Mindfulness and Self-Regulationetect clinically meaningful treatment effects. In order to continue to perform important research in the future, we need to make clinical trial designs more efficient. Through the retrospective statistical analysis of variation in the design of past trials and the prospective comparisons of clinicalMIRE 发表于 2025-3-29 19:31:41
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Handbook of Mindfulness and Self-Regulationnalysis is conducted. At each interim analysis, the trial can stop for futility, stop for efficacy, or continue. The main advantage of group-sequential designs is that the expected number of patients is reduced compared to a design without interim analyses. There are infinitely many possible group-s索赔 发表于 2025-3-30 02:29:49
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