generic
发表于 2025-3-30 09:16:34
http://reply.papertrans.cn/27/2651/265004/265004_51.png
PALMY
发表于 2025-3-30 13:45:38
Temporal and Pharmacokinetic Aspects in Delivery of Peptides and Proteins,ug. When an understanding of how an individual patient will absorb and eliminate a drug is coupled together with knowledge of the pharmacologic effects of a given amount of the drug, a particular dose can be selected that will result in clinical efficacy and minimal toxicity. Such considerations hav
ARY
发表于 2025-3-30 20:29:01
Enzymatic Barriers to Peptide and Protein Absorption and the Use of Penetration Enhancers to Modifythelia that are poorly absorptive, the presence of significant levels of enzymatic activity at various locations between the point of entry into the systemic circulation and the target site of a peptide or protein, the availability of multiple enzymes to degrade peptides and proteins at a given loca
脱毛
发表于 2025-3-30 21:22:00
Intracellular Sorting of Proteins,orm specialized functions, such as oxidative phosphorylation within the mitochondria or ribosome assembly within the nucleolus. How do cells generate and maintain such an asymmetric, highly organized distribution of their proteins? Five major targets of protein transport have been studied in detail:
裙带关系
发表于 2025-3-31 04:40:05
Biodegradable Polymers for Sustained Release of Polypeptides,peptides as well as improvements in techniques leading to total chemical synthesis of lower molecular weight peptides such as ‘Zoladex’ (ICI 118630; D-Ser (Bu.).-Azgly.-LHRH; ‘Zoladex’ is a trade mark, the property of Imperial Chemical Industries PLC). However the therapeutic and commercial potentia
AROMA
发表于 2025-3-31 08:36:21
The Oral Bioavailability of Peptides and Related Drugs,ic applications and to the design of peptide drugs. However a contributing factor to the therapeutic success of a drug is the availability of an oral formulation. For peptides and proteins, oral absorption and bioavailability is generally low (as shown in Table 2) relative to that expected of non-pe
苦恼
发表于 2025-3-31 12:08:38
Oral Delivery of Peptide Drugs,y have shown that peptides can be developed as highly effective therapeutic agents in a number of different areas. As with many other drugs, however, the therapeutic efficacy is often diminished by their inability to reach the site of action in adequate amounts, and the choice of administration rout
压碎
发表于 2025-3-31 17:08:04
http://reply.papertrans.cn/27/2651/265004/265004_58.png
Paraplegia
发表于 2025-3-31 19:47:11
http://reply.papertrans.cn/27/2651/265004/265004_59.png
门闩
发表于 2025-4-1 01:35:04
Microspheres as a Potential Controlled Release Nasal Drug Delivery System,e surface available for drug absorption. Furthermore, the subepithelial layer is highly vascularized with large and fenestrated capillaries specially designed for rapid passage of fluid through the vascular wall (Mygind, 1978). Unlike absorption from the gastrointestinal tract the venous blood drain