FRAX-tool 发表于 2025-3-30 10:11:58
Regulation of Death Receptors,ation. The expression of the members of the death receptor family is tightly regulated and varies among tissues. Dysregulation of death receptor expression is implicated in the pathogenesis of various diseases, including cancer, autoimmune disorders, neurodegenerative diseases, and infections. In thcreatine-kinase 发表于 2025-3-30 13:53:36
Regulation of Trail Receptor Expression in Human Melanoma,s a major determinant of the sensitivity of melanoma cell lines to TRAIL-induced apoptosis. Transcriptional events regulating TRAIL death receptor expression have been the focus of much study, but our investigations point to a more important role for posttranscriptional events in regulation of TRAILFretful 发表于 2025-3-30 18:44:36
Regulation of Death Receptors by Synthetic Retinoids,erentiation, and apoptosis of many cell types (.). Thus, they play important roles in regulating, among other things, embryonic development, hematopoiesis, bone formation, glucose and lipid metabolism, and carcinogenesis (.). Currently, retinoids are used clinically in the treatment of skin disorderPalatial 发表于 2025-3-30 22:36:53
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Proapoptotic Gene Silencing Via Methylation in Human Tumors,de. This process plays a crucial role in the normal life cycle of organisms, facilitating embryonic development, metamorphosis, cellular specialization; maintaining homeostasis (.,.). Apoptosis is characterized by a complex set of tightly controlled biochemical and molecular events leading to cell d浪荡子 发表于 2025-3-31 05:50:50
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Sensitizing Tumor Cells by Targeting Death Receptor Signaling Inhibitors,ctive area of research in the development of novel anticancer therapies. Systemic delivery of FasL causes hepatotoxicity, limiting its use to local administration (.). In contrast, preclinical studies with TRAIL show that systemic delivery of the soluble form is well tolerated in nonhuman primates (