Metastasis 发表于 2025-3-23 09:46:47
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Andrea Bandini,Patrizia Gianni,Enrico Sbarraentail the development of multiple cutaneous and mucous membrane vascular lesions associated with other life-threatening complications. This chapter deals with the clinical and pathologic features of three such conditions, namely, Osler-Weber-Rendu (OWR) syndrome, ataxia-telangiectasia (AT), and Fabry’s disease (FD).模仿 发表于 2025-3-23 22:49:53
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Paget’s Diseasesement membrane of the underlying ducts to the epidermis of the nipple. The second theory, in situ malignant transformation or degeneration from existing cells, postulates that the Paget cell is a malignant keratinocyte in situ; thus, this theory defines Paget’s disease as an in situ carcinoma without underlying cancer of the breast.债务 发表于 2025-3-24 08:57:06
Gardner Syndromes. Interestingly, the cutaneous lesions were not characterized in that report because one family member had expired shortly after having a cutaneous lesion removed, and others in the family were afraid they would meet the same fate if their lesions were removed.DRILL 发表于 2025-3-24 11:29:15
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http://reply.papertrans.cn/27/2640/263956/263956_19.pngEndoscope 发表于 2025-3-25 00:14:26
Mast Cell Disease: Urticaria Pigmentosane c-kit at codon 816. C-kit functions as a transmembrane protein and is involved in signaling cell division when bound to mast cell growth factor. Mutations in the 816 position result in abnormal proliferation of mast cells.