Certainty 发表于 2025-4-1 03:26:36

https://doi.org/10.1007/978-3-030-72711-6ecific interaction appear to be very similar: side-chains from protruding alpha-helices penetrate the DNA major groove and interact with the exposed edges of base pairs. DNA polymerase, on the other hand, contains a very large cleft which is able to nearly surround a double-stranded DNA substrate.
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查看完整版本: Titlebook: DNA-Ligand Interactions; From Drugs to Protei Wilhelm Guschlbauer (Director),Wolfram Saenger (Co Book 19871st edition The Editor(s) (if app