Certainty 发表于 2025-4-1 03:26:36
https://doi.org/10.1007/978-3-030-72711-6ecific interaction appear to be very similar: side-chains from protruding alpha-helices penetrate the DNA major groove and interact with the exposed edges of base pairs. DNA polymerase, on the other hand, contains a very large cleft which is able to nearly surround a double-stranded DNA substrate.