Inordinate 发表于 2025-3-26 21:03:19
Lecture Notes in Computer Sciencecterial-like mode of DNA replication with single origins of replication per chromosome, the majority of species characterized to date possess chromosomes with multiple replication origins. Genetic, structural, and biochemical studies have revealed the nature of archaeal origin specification. RecentNORM 发表于 2025-3-27 01:56:10
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Fazia Aboud,Nathalie Grangeon,Sylvie Norref the replicon. At this stage, the remaining fragments of DNA have to be unwound, all remaining DNA replicated and newly synthesised strands ligated to produce continuous sister chromatids. Finally, the replication machinery has to be taken off, chromatin re-assembled, and entwisted sister chromatidResection 发表于 2025-3-27 14:11:42
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Leonor Melo,Francisco Pereira,Ernesto Costading humans. The . replisome is a large and dynamic assembly comprised of ~50 proteins. The core of the replisome is composed of 31 different proteins including the 11-subunit CMG helicase; RFC clamp loader pentamer; PCNA clamp; the heteroligomeric DNA polymerases ε, δ, and α-primase; and the RPA he傲慢人 发表于 2025-3-27 23:12:07
Lecture Notes in Computer Scienceell cycle but also during the process of development and differentiation. The units of replication timing regulation, known as replication domains (RDs), frequently comprise several nearly synchronously firing replication origins. Replication domains correspond to topologically associating domains (大门在汇总 发表于 2025-3-28 04:46:47
Order Statistics in Artificial Evolutionre activated during a single cell cycle. In addition, the ones that are activated are activated in a sequential order. Why don’t origins of replication normally all fire together? Is this important? And if so, why? Would any order of firing do, or does the specific sequence matter? How is this proceBYRE 发表于 2025-3-28 08:23:32
A Hybrid Evolutionary Algorithm for CSP the vertebrate genome are activated according to a spatiotemporal program. The genome-wide mapping of origins in several model systems has identified G-quadruplexes—higher-order DNA structures formed from G-rich sequences—as potential key regulators of origin activity. Here, I describe genetic expePantry 发表于 2025-3-28 10:53:51
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