现任者
发表于 2025-3-26 22:19:24
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Obstreperous
发表于 2025-3-27 04:46:23
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我不怕牺牲
发表于 2025-3-27 08:14:00
Aortic Response to Various Effects,ells of higher eukaryotes to repair this lesion, nonhomologous end-joining (NHEJ) is the most dominant. The biochemical characterization of NHEJ has significantly benefited from in vitro plasmid end-joining assays that can complement and extend information obtained from genetic studies. There is evi
友好
发表于 2025-3-27 10:09:46
https://doi.org/10.1007/978-1-4684-3243-5seases. Gene targeting approaches are also useful for studying the mechanisms of homologous recombination. We have developed gene targeting methods that we have specifically used to investigate the mechanisms of recombination in cultured mammalian cells. In this chapter, we describe the generation o
无能力
发表于 2025-3-27 15:37:17
William D. Wagner,Thomas B. Clarksonth high reproducibility. Specific nicking and loss of a restricted DNA fragment at the site of induced damage is visualized by Southern blot and quantified against a control; since the blot is gene specific, only the damage of interest is measured. Here we show how the assay may be adapted to assess
ABHOR
发表于 2025-3-27 18:06:24
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饥荒
发表于 2025-3-28 01:08:14
Jack C. Geer,William S. Webster the genome is modulated by the DNA sequence, by DNA methylation patterns, by the transcriptional status of the locus, and by chromatin proteins associated with the DNA. The only method currently available to allow a precise sequence mapping of DNA lesions in mammalian cells is the ligation-mediated
有其法作用
发表于 2025-3-28 03:10:52
Wolfgang Schaper,Dimitri Scholzeous genetic damage has developed. This, in turn, has increased interest in the cellular mechanisms responsible for tumorigenesis, and the need to develop experimental methodologies to investigate these mechanisms. DNA represents a most important cellular target for ultraviolet radiation (UVR), lead
Ibd810
发表于 2025-3-28 09:36:59
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arthroscopy
发表于 2025-3-28 12:03:49
Eric Allaire,Peter Libby,Alexander W. Clowesver other analytical procedures currently used to measure DNA damage including adaptability, sensitivity and selectivity. This combination of attributes allows for the development of powerful analytical techniques to visualize and quantify specific types of DNA damage in cells and organisms exposed