mighty
发表于 2025-3-23 10:26:46
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羊齿
发表于 2025-3-23 17:42:46
Structure and Function of TET Enzymes,omethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). TET enzymes and oxidized 5mC derivatives play important roles in various biological and pathological processes, including regulation of DNA demethylation, gene transcription, embryonic development, and oncogenesis. In thi
Rebate
发表于 2025-3-23 18:42:04
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nascent
发表于 2025-3-23 23:56:55
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Provenance
发表于 2025-3-24 05:46:29
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精密
发表于 2025-3-24 08:03:43
DNA Methyltransferase Inhibitors: Development and Applications,thyltransferases (DNMTs) is a powerful strategy to modulate, restore, or reduce DNA methylation. In this chapter, we will present examples of inhibitors of DNMTs (DNMTi) and review the fields of applications of DNMTi mainly as therapeutic molecules, for example, in cancers, cardiovascular or neurolo
无思维能力
发表于 2025-3-24 13:30:36
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休息
发表于 2025-3-24 18:29:18
Engineering and Directed Evolution of DNA Methyltransferases,ique and selective manner. Here, we review various aspects of MTase engineering, both methodological and conceptual, and also discuss future directions and challenges. Bacterial MTases that are part of restriction/modification (R/M) systems offer a convenient way for the selection of large gene libr
Lipohypertrophy
发表于 2025-3-24 20:05:03
DNA Labeling Using DNA Methyltransferases,cofactor S-adenosyl-L-methionine (AdoMet). Although DNA methylation plays important roles in biological signaling, the transferred methyl group is a poor reporter and is highly inert to further biocompatible derivatization. To unlock the biotechnological power of these enzymes, two major types of co
Curmudgeon
发表于 2025-3-25 00:46:54
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