chronicle 发表于 2025-3-25 03:21:43
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Archaeoastronomy in the Roman Worldbioassay system through either a mitogenic or mutagenic mechanism ., most of the known potent carcinogens are strong mutagens, and it is these genotoxic carcinogens that are the subject of this chapter.Redundant 发表于 2025-3-25 12:59:15
https://doi.org/10.1007/978-3-319-21885-4rder to repair, recover, and survive, mammalian cells must first recognize this DNA or membrane damage. Otherwise, the consequences of DNA damage tolerance have been shown to lead to increased rates of mutation and ultimately carcinogenesis, as observed in DNA mismatch repair-deficient cells ..切掉 发表于 2025-3-25 16:57:18
https://doi.org/10.1007/978-3-319-21885-4on appears to account for most changes in gene expression, changes in mRNA . or in protein stability (e.g., p53) also can contribute to the changes in protein levels that occur in response to genotoxic stress.落叶剂 发表于 2025-3-25 22:19:45
Exogenous Carcinogen-DNA Adducts and Their Repair in Mammalian Cells,bioassay system through either a mitogenic or mutagenic mechanism ., most of the known potent carcinogens are strong mutagens, and it is these genotoxic carcinogens that are the subject of this chapter.fixed-joint 发表于 2025-3-26 02:15:08
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Role of HMG and Other Proteins in Recognition of Cisplatin DNA Damage, CDDP) to DNA. Once bound to DNA, DRPs are likely to have a major influence on the subsequent processing of specific types of DNA damage. For example, DRPs may influence the kinetics of repair of particular DNA abducts and, hence, determine the physiological response of cells to specific DNA-damaging agents.Forsake 发表于 2025-3-26 17:09:54
Long-Term Human–Environment Relationsrmed is a potent mutagenic substrate for DNA synthesis, since it can be incorporated opposite adenine as well as cytosine in DNA, at almost equal efficiencies .. In this case, both types of transversions, A-T to C-G and G-C to T-A, would be induced ..