Meander 发表于 2025-3-23 11:22:04
http://reply.papertrans.cn/25/2427/242686/242686_11.pngparasite 发表于 2025-3-23 16:44:01
Georg Petroianu,Peter Michael Osswaldious forms of vesicle transport, nuclear transport and actin cytoskeleton regulation (Bourne et al. 1990). These small GTPases (about 21 kDa) act as molecular switches that are active when they are GTP-bound, and inactive when GTP is converted to GDP, due to their intrinsic GTPase activity (Boguskidry-eye 发表于 2025-3-23 20:43:47
http://reply.papertrans.cn/25/2427/242686/242686_13.pngCanary 发表于 2025-3-23 23:12:41
Georg Petroianu,Peter Michael Osswaldstate. Until recently, members of the Rho-subfamily were believed to be primarily involved in the regulation of cytoskeletal organization in response to extracellular growth factors. However, studies from numerous groups over the past few years have revealed that the Rho-GTPases play crucial roles i启发 发表于 2025-3-24 06:19:29
Georg Petroianu,Peter Michael Osswaldtransduction leading to changes in membrane structures and cytoskeletal reorganisation associated with changes in cell shape. Like other Ras-related proteins, Rho GTPases are thought to adopt either an active GTP-bound conformational state or an inactive GDP-bound state. Although cycling between the完成 发表于 2025-3-24 07:18:04
http://reply.papertrans.cn/25/2427/242686/242686_16.pngTremor 发表于 2025-3-24 12:23:03
Philippe JeanteurThis volume summarizes the current understanding of the Rho family of signal transduction molecules使纠缠 发表于 2025-3-24 17:47:54
Progress in Molecular and Subcellular Biologyhttp://image.papertrans.cn/d/image/242686.jpghandle 发表于 2025-3-24 20:47:54
0079-6484 ffected by signals in the form of small molecules outside the cell. These changes can then alter the shape or adhesiveness of the cell. This volume centers particularly on one family of cellular proteins which transmit these signals, the Rho Ras-like GTPases, and examines their role in normal cellulFissure 发表于 2025-3-25 02:31:14
Georg Petroianu,Peter Michael Osswaldoteins such as catenins and talin Takeichi 1990Gumbiner 1996). Cell adhesions are also dynamically reorganized during cell movement and mitosis. However, until recently little was known about the signal transduction pathways which regulate the reorganization of the cytoskeleton and cell adhesions.