forager
发表于 2025-3-25 03:27:52
Environment, Genes, and Mental Healtht possess inflammatory potential. We have demonstrated that certain of these cytokines can activate MAP kinases and the pathway leading to NF? B, via known IL-1R family members. Moreover, when overexpressed in skin, they are capable of causing an inflammatory skin condition resembling that seen in human disease.
insurrection
发表于 2025-3-25 08:25:06
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spondylosis
发表于 2025-3-25 12:17:49
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本土
发表于 2025-3-25 19:50:23
Conference proceedings 2006-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that target cytokines directly, strategies that target cytoki
inveigh
发表于 2025-3-25 20:08:37
Induction of Immunity and Inflammation by Interleukin-12 Family Members,ronic inflammation through induction of IL-17 and direct activation of macrophages. Very recently, IL-27 was found to exert not only a pro-inflammatory Th1-enhancing but also a significant anti-inflammatory function.
Prosaic
发表于 2025-3-26 01:24:53
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Gobble
发表于 2025-3-26 05:41:00
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沙漠
发表于 2025-3-26 11:56:04
Anticipation Across Disciplinesronic inflammation through induction of IL-17 and direct activation of macrophages. Very recently, IL-27 was found to exert not only a pro-inflammatory Th1-enhancing but also a significant anti-inflammatory function.
Myosin
发表于 2025-3-26 16:01:26
Anticipation Across Disciplines, such treatment increases the risk of infections, certain type of cancers, and cardiotoxicity. Thus blockers of TNF that are safe and yet efficacious are urgently needed. Some evidence suggests that while the transmembrane form of TNF has beneficial effects, soluble TNF mediates toxicity. In most c
Physiatrist
发表于 2025-3-26 20:20:45
,Inhibition of IFN-γ as a Method of Treatment of Various Autoimmune Diseases, Including Skin DiseaseIFN can be therapeutic. In 1989, we proposed removing tumor necrosis factor (TNF)-α together with certain types of IFNto treat variousADs. We found IFN in patients with different ADs and conducted the first clinical trial of ACT in 1975. Anti-IFN-γ and anti-TNF-α work in similar ways, but the latter